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"Cross Road Blues" is a song by delta blues singer Robert Johnson; released on a 78 rpm record in 1936 by Vocalion Records, catalogue 3519. The original version remained out of print after its initial release until the appearance of The Complete Recordings in 1990. In 1961, producer Frank Driggs substituted the previously unreleased alternative take on the first reissue of Johnson's work, the long-playing album King of the Delta Blues Singers. Because of the historical significance of "Cross Road Blues", it was inducted into the Grammy Hall of Fame in 1998.

On March 10, 1968, Cream recorded a live version "Crossroads" from their performance at the Winterland Ballroom in San Francisco. The version was arranged by guitarist Eric Clapton, and included two lines borrowed from Johnson's "Traveling Riverside Blues." The song features an eight-note guitar riff and has both major and minor scale centers. Cream's cover of the song was placed at #409 on the 2004 List of Rolling Stone's 500 Greatest Songs of All Time, and #3 on the 2008 Greatest Guitar Songs of All Time. The song also ranks #10 on Guitar World's 100 Greatest Guitar Solos

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